Intracytoplasmic sperm injection (ICSI)

Intracytoplasmic sperm injection (ICSI) is an advanced form of IVF, where a single sperm is injected into an egg to achieve fertilisation.

It is advised in male factor infertility, including in severe cases of azoospermia (complete absence of sperm in the ejaculate) where surgically retrieved sperm is used.

The patient will follow a similar care pathway as in IVF till egg collection. The laboratory process will now vary in that the eggs are cleaned and checked for maturity, and a single sperm is injected into the egg under high power microscopy.

Essentially there are several stages of ICSI treatment:

    • Stimulation of the ovaries by gonadotrophin injections to produce eggs
    • Collection of the eggs from the ovaries, usually performed under sedation
    • Preparation of sperm sample obtained on the day of egg collection
    • Eggs are cleaned to check for maturity and a single sperm is injected into each mature egg.
    • Replacement of the fertilised eggs (embryos) into the womb

    There are several regimens that can be used for ovarian stimulation, for example commonly known as long and short protocols.  Mrs Gordon will advice you on the most appropriate stimulation regimen for you based on your history, ovarian reserve and any potential risks involved.  Care provided is always evidenced based and Mrs Gordon will also discuss with you the necessity of any adjuvant procedures such as Endometrial Scratch, use of testosteron gel, steroids etc.

All consultations and monitoring scans will be undertaken at the Spire Bristol Hospital under the consultant care of Mrs Gordon. Egg collection, embryo transfer and any freezing required are carried out at the licensed centres London Women’s Clinic Wales and Bristol Create Fertility Clinic.   All cycles will be closely monitored and supervised by the consultant Mrs Gordon to provide you individualised care.